One of the largest independent provider of contract laboratory services in India & abroad with full range of accredited(CIB) GOI,NABL, GMP, EPA & OECD compliant for Chemical, toxicological, microbiological, food analyses, Biotechnological & Environmental Impact analysis following all sophisticated advanced facilities with the supervision of expertise of National & International Repute under one roof especially located in the eastern & N.E region of country. Services would be provided primarily for the Agrochemicals, plantations (Tea & others), food & processed foods and pharmaceutical & herbal industries, Entrepreneurs, Growers & cultivators. HIGHEST SCIENTIFIC STANDARDS, SPEEDY SERVICE AND COMPETITIVE PRICES ARE KEY ELEMENTS IN OUR COMMITMENT TO PROVIDE A TOTAL QUALITY SERVICE. Welcome to this International Contract Research Laboratory Services Website. http://www.krishirasayan.com. It has the commitment for offering some social services especially for the lower level beneficiaries in the discipline of Agriculture, Horticulture, Agro forestry, health care & in alternative medicine, High standards sophisticated facilities to be created under one roof under the supervision of National & International stalwart experts in various disciplines. This contract research laboratory has thus been proposed with the following objectives: Objectives: I. To provide R&D services of international standards at cost-effective rates. For the following biological based Industries/Entrepreneurs: Agrochemical Pharmaceutical Chemical Biotech industries In the broad discipline of: Chemistry (Analytical & development) Toxicology Microbiology Biotechnology II. Regulatory and non-regulatory studies following guidelines of all National & International regulatory authorities: Central Insecticides laboratory (CIB) GOI NABL (ISO170025),GOI GLP OECD EPA,USA FAD,USA Japan regulatory Authority. III. Quality standards and Quality Assurance programs. A. Analytical chemistry services include: Physiochemical properties of chemicals, adjuvant & other formulating chemicals Product specification, Method of analysis (development & validation), Analytical test report , Identification & quantification of identifiable impurities, Shelf-life studies, Container content compatibility studies, Metabolism (plant, water & soil). Bioefficacy, Phytotoxicity, compatibility & effect on beneficial micoflora for chemicals under field condition Residue analyses & dissipation of parent compound in all biological substrates. Metabolites in plant, food, animal tissues, diary products & environmental samples (water, soil), Proximate analysis of proteins, fats, carbohydrates, oils, fatty acids, crude fibre & energy value, food additives, analysis of toxicants- toxic trace metals, metal contaminants, Mycotoxins & aflatoxins in foods, agricultural products & other biological substrates samples. Analysis of POPs, PAH, PCB, PBB, Dioxins & other organic pollutants. Method Development and Validation. B. Toxicology & Cell Biology -Aquatic & terrestrial Ecotoxicology Acute toxicity in rat (oral, ip, im, iv, subcutaneous) Acute toxicity in mice (oral, ip, im, iv, subcutaneous) Acute toxicity in rat (dermal) Acute toxicity in rat (inhalation) Skin irritation / corrosion Eye irritation Skin sensitization 7, 14, 28 day rodent toxicology studies with backup of chemical analysis and clinical pathology Histopathology - necropsy, slide preparation & evaluation and peer review Mutagenicity tests ( e.g. in vitro Ames & Chromosomal Aberration and in vivo Micronucleus in mice ) Batch Testing of Vaccines 5 Batch Analysis. Rodent, non-rodent toxicological studies Avian toxicological studies Aquatic and fish toxicological studies Method Development and Validation. C. Microbiology: Microbial food safety determinations for Agri/horti raw & processed produce. Pathogen testing with species identification, Preservative efficacy testing (PET), Bacterial endotoxin testing, CFU( Colony Forming Units) Counts, Viable cell count, Moisture content, Suspensibility, Pathogenic contaminants, Antagonistic capability, pH. Microbial contamination/ bioburden testing irradiation dose setting determination studies (ISO 11137), Purified water & water for injection, Antibiotics assay, Environmental hygiene monitoring, Shelf-life determination, Water testing, sterility testing, Services. Method Development and Validation Biotechnology: DNA fingerprinting analysis for seed testing. Molecular Biology techniques for identification of viral diseases in Pants, animals. Trnasgenic develomemnt Biosafety analysis for GM crops as pr regulatory bodies for certification. Method development of Bioremediation of Contaminants. ELISA quick testing assay for analysis of chemicals in biological substrates. Storage and handling of food & its preservation. Quality assurance & food safety Pharmaceuticals Quality Standardization Herbal Quality standardization. Method Development and Validation INFRASTRUCTURES FACILITIES TO BE CREATED: A. Chromatography: Gas Chromatography with Detectors (ECD, FID, NPD, FPD, TID etc) High Performance Liquid Chromatography with Detectors (UV & Fluorescence) Thin Layer, column & Ion exchange Chromatography. High Performance Thin layer Chromatography Gas Chromatography- Mass Spectra (GC-MS, GC-MSMS) Liquid Chromatography- Mass Spectra (LC-MS, LC-MSMS) B. Spectrophotometry & centrifugation: UV-VIS Spectrophotometer Ultra Centrifuge Cooling Centrifuge C. Advance Extraction, cleanup & concentration facilities. Animal facilities & ethics: All animal based experiments will as per CPCSEA norms and formation of Institutional Animal Ethics Committee in addition to AAALC accreditation. Krish Biotech has animal house space, for all animal studies. It conforms to recommended quality standards, animal husbandry and humane treatment of animals, as per CPCSEA guidelines. Toxicology /Histopathology: Auto Analyzer Inhalation toxicity chamber Homogenizer (tissue) Rotary Micotome Rota rod Analgesiometer Plethysmoneter Polygraph/ Polyrite apparatus D. Microbiology: Laminar Flow. Membrane filtration unit. Purified water system Tissue culture unit with Illuminated racks. BOD Incubator, Autoclave & more Special apparatus E. Microscopy: Normal High Precision microscope, Phase contrast Microscope, Scanning Electron microscope F. Biotechnology: Polymerase Chain Reaction unit GelDoc system Vertical, 3D and submarine with power pack (vertical & Horizontal)system. Deepfrdger (-70°C to -25°C) Gel Documentation system. Elisa reader Multi channel and single single channel accu pipett Pre fabricated Tissue culture room with timer controlled lighting facilit Pico drop for DNA quantification Advisors (Hon): Prof. Ashim Chowdhury, FNAAS, FAScT, FSPS, FISAC. Sr Fulbright Scholar-USDA, USA, Post Doc. Germany. under DAAD programme, Visiting Scientist In Germany, USA, Canada, UK, Belgium, France, China, Taiwan under DAAD, INSA, Personal Invitation, BCPC-UK. Member SMPB, Dept of health& FW, Govt of W.B., Member Technical advisory committee, Farm Modernization committee& Technical support Group, FPI & H Deptt, Govt of Kolkata, W.B. Dr. T.P Suresh xxxxxx Dr. Renuka Sengupta- xxxxxxx. Dr N.P Agnihotri ,Fomer HOD, Agril chemicals, Co-ordinator, AICRP Pesticides Residue, IARI, Former Director, Jai Foundation, Dr B.V David, Former Director, Jai Foundation. Dr.Madhubangopal. IARI.ICAR. Dr.B.C pal, Senior Scientist, IICB, CSIR, Kolkata Dr. N.K Roy, FNAAS Former HOD, Coordinator, Pesticides residue, IARI,ICAR. Dr. P. Dureja, FNAAS, HOD,IARI Dr.T.K Audhya ,Director, FNA,FNAAS.Cuttack Prof. B. Mondal ,FNAAS ,kalyani. Prof.A.K somchaudhury, Former HOD, Ag Entomology,BCKV.Kalyani Dr A.K Chakrabarty, Ex Teacher Pharmacology & Toxicology, WBFAS, Dr. J.K Malik, Prof & HOD, Pharmacology, IVRI(ICAR), Ijjatnagar Dr.J.K Tarafdar, BCKV, Kalyani Dr S.K manna, Pharmacology& Toxicology, Deptt of vet & animal sc, Govt of West Bengal sc Dr. Bera, Research Director, Tea Board, Kolkata. Dr M.K Hazarika, TRA. Dr Brajendra Singh former CIB(Ent). Dr.B.S parmerFNAAS,FSPS, Former HOD-Agrichemicals,IARI,ICAR.

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